Ah, Clomid. I've avoided you for so long, but now it seems our time has come. I still don't think I "need" you, but you might help me out, so here goes nothing.
Clomid (full name: clomiphene citrate), much like marijuana, is a gateway drug. Ha ha. Not really. I mean, it could be. Heck, let's start over. Clomid is the first drug that a woman will take when fertility drugs come into the question. Here's the thing about Clomid and
me. I don't want to take it because there isn't anything wrong with me. My cycle is practically textbook. I do everything right. I produce cervical fluid. I produce a healthy uterine lining. I produce a dominant follicle. I ovulate. I do all the things a girl should do. And I have a thing about taking meds. I don't like to do it. I don't even like to take aspirin when I have a headache.
Forgive me right now, because this post will be far from linear. I can't write about this in a cohesive fashion, because my feelings about Clomid are not cohesive.
Clomid is typically given to women who have a problem with their cycle.
The Two Big Problems are 1) failure to ovulate, and 2) short luteal phase. I have neither of these problems. So why does my doctor want me to take Clomid?
Here's what happens in a normal, unmedicated cycle like mine. The follicle stimulating hormone (FSH) starts, well, stimulating the follicles in a woman's ovaries. Somewhere between 10-20 come to life and start growing. Somehow, and no one knows exactly how this happens, one of the follicles is "picked," and it become dominant. It grows bigger and bigger, and it starts to release estrogen. Now, as the estrogen circulates through a woman's body, the hypothalamus (which controls the FSH) says, "Hey, my work here is done. A good folli is out there, juicing up the place with estrogen. I'll stop with this FSH stuff now." The dominant follicle keeps on cooking. It no longer needs the FSH to grow. The other follicles, however, are too small and weak to keep going without the FSH, so they fade back, leaving one ripe and juicy follicle, which will later produce an egg to (hopefully) get fertilized. It is because of this process that humans almost always have one child at a time.
Now, here's what Clomid does. It masks the estrogen produced by the dominant follicle. "So what?" you say. Well, here's what. Since the hypothalamus never receives the news that there is a dominant follicle already, it keeps on sending out the follicle stimulating hormone. Those follicles that would normally wilt back and go bye-bye keep on chugging along until the point where they, too, no longer need the FSH to keep going.
"What does this mean?" It means two things. For one, it means that I will likely produce more than one viable egg this cycle. Secondly, all of the eggs (I'll tell you how many on cd12 after my ultrasound) will probably
not be released simultaneously. This means that there is a wider margin for error with the IUI. Miss one egg? Well, another is coming along behind it. Or if two or more are around when the sperm is around, it gives the sperm "more targets" as my doctor put it. Here's another common phrase: "More eggs, more chances."
"More eggs? More babies?" Yes, there is a higher chance of having twins on a Clomid cycle--but not excessively high. About 10% on Clomid vs. under 2% au natural. As for triplets or more, the chances of that are not any higher than the general population (somewhere under 1%, I believe).
"Wow, all that sounds great! What's the problem?" Well, there are some side effects. Namely, some women can get a little crazy on Clomid. I don't really need any help in that department, thank you very much. Other common side effects include hot flashes, sleeplessness, headaches, and intense ovulatory pain. I don't look forward to any of those things. And let's not forget that
my cycle is just fine the way it is.
"Right, I see your point. Your cycle is fine. So why take Clomid?" For the simple reason that it should increase my chances of conceiving. Although it's been fun
not getting pregnant, I think I'm ready to actually be pregnant now. I'll give Clomid a few tries, and see what happens. But I'm not exactly happy about it.